─ Cliff Mad Honey Index
Research &
References
The peer-reviewed literature behind everything we publish: cited studies, annotated sources, and methodology notes.

Every claim in the Cliff Mad Honey Index is backed by published science. This section is an annotated library of the peer-reviewed studies, clinical case series, and scientific papers we reference across the site. We do not conduct original research. We read, verify, and clearly explain what the existing literature says.
All References
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Source paper Jansen SA, Kleerekooper I, Hofman ZLM, Kappen IFPM, Stary-Weinzinger A, van der Heyden MAG. Grayanotoxin Poisoning: ‘Mad Honey…
Dhurba Saud
Jun 5, 2026

Source paper Aryal M. Grayanotoxins in Mad Honey: Mechanisms of Toxicity, Clinical Management, and Therapeutic Implications. Journal of Applied Toxicology.…
Dhurba Saud
Jun 4, 2026

Source paper Ullah S, Khan SU, Saleh TA, Fahad S. Mad honey: uses, intoxicating/poisoning effects, diagnosis, and treatment. RSC Advances.…
Dhurba Saud
Jun 3, 2026

Source paper Ahn S-Y, Oh S, Woo S, Kim C-H, Kim J-H. Detection and Simultaneous Quantification of Three Grayanotoxins in…
Dhurba Saud
Jun 2, 2026

Ethnographic and ethnobotanical documentation of deli bal use in Anatolian communities represents an important body of knowledge that predates and…
Dhurba Saud
Apr 23, 2026

Grayanotoxin poisoning from mad honey produces a characteristic hemodynamic profile (bradycardia, hypotension, and varying degrees of atrioventricular conduction block) that…
Dhurba Saud
Apr 23, 2026

The quantification of grayanotoxins in commercial honey presents specific analytical challenges that make method selection and validation critical to the…
Dhurba Saud
Apr 23, 2026

Of the approximately 700 Rhododendron species recognised by botanists, not all produce grayanotoxins, and among those that do, concentrations vary…
Dhurba Saud
Apr 23, 2026

Grayanotoxin I (GTX I) binds to receptor site 2 on voltage-gated sodium channels (VGSCs), the same binding site targeted by…
Dhurba Saud
Apr 23, 2026

The majority of published clinical case series on mad honey poisoning originate from emergency departments in northeastern Turkey, particularly hospitals…
Dhurba Saud
Apr 23, 2026
