CliffMadHoneyIndex

The Mad Honey Toxidrome: A Systems-Level Look at Cardiovascular and Neurological Effects

Anatomical heart model with glowing amber ECG trace waves passing through it on dark blue background, illustrating grayanotoxin cardiovascular effects

The physiological impact of mad honey is not confined to a single organ system. Grayanotoxins, by virtue of their action on voltage-gated sodium channels expressed across multiple tissue types, produce a constellation of effects spanning the cardiovascular system, the autonomic nervous system, the peripheral sensory nervous system, and the gastrointestinal tract. Understanding each system’s contribution […]