CliffMadHoneyIndex

The Mad Honey Toxidrome: A Systems-Level Look at Cardiovascular and Neurological Effects

Infographic showing grayanotoxin Site 2 sodium channel binding causing one mechanism affecting three body systems: cardiovascular (bradycardia, hypotension, AV block), neurological (dizziness, perioral tingling, fainting) and gastrointestinal (nausea, vomiting, salivation)

A toxidrome is the recognizable cluster of signs and symptoms that a particular toxin, or class of toxins, reliably produces. Grouping effects into a toxidrome lets a clinician move from a scatter of individual complaints toward a single explanation, and grayanotoxin produces one of the more distinctive examples in plant toxicology. The mad honey toxidrome […]