Rhododendron honey Archives - Cliff Mad Honey Index

Grayanotoxin LD50: Lethal Dose Data, Route Effects, and What Animal Studies Cannot Tell You About Human Risk

$CMHI mad honey poisoning treatment protocol flowchart showing four steps: IV saline for hypotension, atropine 0.5 to 3 mg IV for bradycardia and AV block, catecholamine support for refractory hypotension, and temporary pacemaker for complete AV block$

The LD50, lethal dose 50 percent, is the amount of a substance required to kill 50 percent of a test population under specified experimental conditions. It is a standard measure of acute toxicity used to compare compounds and establish hazard classifications. For grayanotoxin, published LD50 data exist in rodent models across multiple isoforms and routes […]

Grayanotoxin in Mad Honey: What the Research Says About Concentration & Safety

Dark amber mad honey jar with honey dipper dripping honey, surrounded by glowing teal molecular structures on deep navy background

Companion references: the grayanotoxin glossary defines every term used here, and the mad honey fact sheet for journalists collects the citable figures with their sources. MEDICAL DISCLAIMER This page is for educational purposes only and is not medical advice. Mad honey contains grayanotoxin, which can cause serious adverse effects, including cardiovascular events. If you experience […]

Tag: Rhododendron honey

Grayanotoxin LD50: Lethal Dose Data, Route Effects, and What Animal Studies Cannot Tell You About Human Risk

Grayanotoxin in Mad Honey: What the Research Says About Concentration & Safety