CliffMadHoneyIndex

Mad Honey Effects on the Body: A Complete Breakdown

Weathered hands presenting open glass jar of dark amber mad honey toward camera against dark background

The effects of mad honey on the body are a direct consequence of grayanotoxin I (GTX I) and grayanotoxin III (GTX III) binding to voltage-gated sodium channels across multiple tissue types. These channels govern the electrical signalling of cardiac muscle, smooth muscle, and neurons. Under normal conditions, they open briefly in response to a voltage […]