How Grayanotoxin Levels Are Measured in Mad Honey: What a 2022 LC-MS/MS Study Found About Batch Variation

Mad honey is often discussed as if it were one chemically stable product. This paper shows why that is misleading. In 2022, researchers developed and validated a liquid chromatography–tandem mass spectrometry (LC-MS/MS) method to quantify grayanotoxin I (GTX I) and grayanotoxin III (GTX III) in honey, then applied that method to 60 mad honey samples […]
The Ancient History of Mad Honey: From Warfare to Medicine

Introduction Mad Honey, with its intoxicating properties, is not a modern discovery. Its unique effects have been documented for millennia, weaving a rich tapestry of history that spans ancient warfare, traditional medicine, and even culinary curiosity. This post explores the fascinating historical journey of Mad Honey. Ancient Anatolia and the “Honey of Madness” The earliest […]
